For Seniors, Under-graduate, Post Graduate Students it could be a Quiz, Event with Multiple Choice Questions type. For teenagers it could be class quiz format (Students striking Answers to Questions asked related to their Subjects). A variation known as kukuba increased the scope of the game. If you are playing it with kids then you can play by this Number method, Picture method etc.
Generally it is played with Numbers being called out and user strike out Numbers on their Tickets. Tamobla/Houzee can be played in different ways depending on target audience.